First Affiliated Hospital of Wenzhou Medical University Rövid összefoglaló In view of the fact that there is currently no effective antiviral therapy, the prevention or treatment of lung injury caused by COVID can be an alternative target trachealis papillomatosis current treatment.
Microdirect Laryngoscopy with KTP Laser Ablation of Laryngeal Papillomas
There is currently no effective treatment method, which may be related to the excessive immune response caused by cytokine storm.
This study will evaluate thalidomide combined with low-dose hormone adjuvant therapy for severe COVID Patient effectiveness and safety. Részletes leírás Thalidomide has been clinically reported, and combined with antiviral drugs and other conventional treatments have achieved good results in the treatment of severe H1N1, especially after the death of a young severe patient.
After the addition of thalidomide, the reported 35 patients did not Deaths. Subsequent basic research at Fudan University confirmed that thalidomide can treat H1N1 lung injury. And think that the combination with antiviral drugs may be a better alternative strategy trachealis papillomatosis H1N1 before the vaccine is successfully developed.
In view of the fact that there is currently no effective antiviral therapy, the prevention or treatment of lung injury caused by COVID can be an alternative target for current treatment. It has been reported that thalidomide as an immunomodulatory agent for the treatment of IRIS is effective. Although the death rate of COVID infected persons is not high, their rapid infectiousness and the lack of effective antiviral treatment currently have become the focus of the national and international epidemic.
Thalidomide has been available for more than sixty years, and has been widely used in clinical applications. It has been proved to be safe and effective in IPF, severe H1N1 influenza lung injury and paraquat poisoning lung injury, and the mechanism of anti-inflammatory and anti-fibrosis is relatively clear. As the current research on COVID at home trachealis papillomatosis abroad mainly focuses on the exploration of antiviral efficacy, this study intends to find another way to start with host treatment in the case that antiviral is difficult to overcome in the short term, in order to control or relieve lung inflammation caused by the virus To improve lung function.